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Wednesday, 3 September 2008. Friday, 15 August 2008. Stromedix Receives Orphan Drug Designation For STX-100 In Chronic Allograft Nephropathy. STX-100 is a novel humanized monoclonal antibody licensed in 2007 from Biogen Idec. STX-100 targets integrin? Stromedix, based in Cambridge, Massachusetts, is a biotechnology company foc.