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Sunday, June 10, 2012. SIGNS AND SYMPTOMS OF HERPES IN WOMEN. Once a woman has contracted genital herpes , the signs and symptoms are varied and often mistaken for other diseases or infections. This makes diagnosing genital herpes in women more difficult and, therefore, makes treatment more difficult. The signs and symptoms of genital herpes in women often mimic the signs and symptoms of other various female disorders. Because of this, it is very difficult to diagnose genital herpes in women.