Thoery of distillation of binary mixtures. Clasification and study of distillation equipment used for simple, vacuum, steam, reflux distillation, separation of azeotropes. What are the merits of boiling point diagram of a binary mixture? Write down the procedure of calculating equilibrium data of a binary mixture from its relative volatility value. Explain the method of azeotropic distillation in industrial scale. What is relative volatility? In a c.

Distillation may be defined as the separation of the constituents of a mixture including a liquid by partial vaporization of the mixture and separate and collect the vapor. One liquid from non-volatile impurities.

May be monophasic or biphasic. For internal or external use.

Distribution in blood, cellular distribution drug penetration to CNS. Drug metabolism, plasma-protein binding and its effect on drug disposition. Illustrate the different routes of drug degradation. Suggest the means for protection of drugs. Why is distribution of a drug not uniform throughout the body? Discuss the factors affecting drug distribution.