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Chondral and osteochondral lesions are notoriously difficult to treat due to the poor healing capacity of articular cartilage. In fact, the ultimate destiny of such lesions, if left untreated, is disabling pain and osteoarthritis. Scaffold for one-step surgical treatment of chondral and osteochondral defects. Monday, 17 August 2015. Is not approved for sale in the US. Engineered by Gruppo 4 s.