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Principles, materials and equipment involved in drying and mixing of powders, granulation and compression of tablets. Layout of a tableting section. Principles of refrigeration-air conditioning, humidification and dehumidification and fluidization as applied to the manufacturing of tablets. Quality control and standards of coated dosage forms.
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Factors affecting drug absorption from rectal suppositories, suppository bases, preparation of suppository, packing and storage. 1 Define suppositories and displacement value. 2 Discuss different suppository bases. 4 Give the ideal properties of suppository bases. 5 Discuss the problems encountered in manufacturing of suppositories such as hygroscopicity, incompatibilities, viscosity etc.